hrp0082fc2.3 | Bone & Mineral | ESPE2014

Calcium Homeostasis in Adolescents with β-Thalassemia Major: Effect of i.m. Injection of a Megadose of Cholecalciferol

Elkholy Mohamed , Elalfy Mohsen , Hamza Rasha , Mahmoud Nermine , Saleh Mohamed , Elsedfy Heba

Background: The etiology of bone disease in thalassemic patients is multifactorial. Factors such as hormonal deficiency (especially gonadal failure), bone marrow expansion, increased iron stores, desferioxamine toxicity, calcium, and vitamin D deficiency seem to have a serious impact on impaired bone metabolism in this disease.Objectives: To estimate the frequency of calcium homeostasis abnormalities in adolescent thalassemic patients, and to investigate...